Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | AKT2 | P31751 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334428 | 0.92 | TSPO (0.48) | LMNAAKT1AKT2GABRA2GABRB2 | |
| SCHEMBL5337099 | 0.82 | SMN1; SMN2 (0.44) | KDM4EHPGDLMNAAKT1AKT2 | |
| SCHEMBL5341752 | 0.80 | AKT1 (0.53) | LMNAAKT1AKT2GABRA2GABRB2 | |
| SCHEMBL5346366 | 0.78 | NPC1 (0.53) | KDM4EALDH1A1HPGDLMNAGABRA2 | |
| SCHEMBL5352452 | 0.74 | SLC2A1 (0.63) | KDM4EALDH1A1HPGDLMNAAKT1 | |
| SCHEMBL5343937 | 0.74 | CDH1 (0.46) | LMNAAKT1AKT2NPSR1CYP3A4 | |
| SCHEMBL5344445 | 0.74 | AKT1 (0.66) | AKT1AKT2GABRA2GABRB2CHRNA7 | |
| SCHEMBL5343352 | 0.73 | AKT1 (0.49) | KDM4EALDH1A1HPGDLMNAAKT1 | |
| SCHEMBL9911936 | 0.72 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDLMNAGABRA2 | |
| SCHEMBL12940160 | 0.72 | NPC1 (0.54) | KDM4EALDH1A1HPGDLMNAGABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |