Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357335 | 0.92 | KDM4E (0.48) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5341752 | 0.88 | AKT1 (0.53) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5343937 | 0.83 | CDH1 (0.46) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5352452 | 0.82 | SLC2A1 (0.63) | TSPOLMNASLC2A1CYP1A2CYP2C9 | |
| SCHEMBL5344445 | 0.82 | AKT1 (0.66) | SLC2A1CYP1A2CYP2C9CYP2C19GABRA2 | |
| SCHEMBL5343352 | 0.81 | AKT1 (0.49) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5342475 | 0.78 | AKT1 (0.59) | CYP3A4SLC2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5339747 | 0.77 | POLB (0.50) | TSPOGMNNLMNAPOLBCYP3A4 | |
| SCHEMBL5341342 | 0.76 | ALPL (0.49) | POLBCYP3A4NPSR1CYP1A2CYP2C9 | |
| SCHEMBL5340780 | 0.76 | AKT1 (0.59) | SLC2A1CYP1A2CYP2C9CYP2C19GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |