Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | PRKX | P51817 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357501 | 0.90 | MT-CO2 (0.83) | MT-CO2KMT2AMEN1CXCR2SIRT2 | |
| SCHEMBL10980741 | 0.84 | MT-CO2 (0.89) | MT-CO2KMT2AMEN1CXCR2SIRT2 | |
| SCHEMBL12204389 | 0.84 | MAPK1 (0.63) | KMT2AMEN1MAPK1ROCK2RPS6KA5 | |
| SCHEMBL10836939 | 0.83 | MEN1 (0.54) | MT-CO2KMT2AMEN1MAPK1CXCR2 | |
| SCHEMBL28674998 | 0.82 | MT-CO2 (1.00) | MT-CO2KMT2AMEN1CXCR2SIRT2 | |
| SCHEMBL10837292 | 0.82 | HPGD (0.59) | MT-CO2KMT2AMEN1MAPK1POLB | |
| SCHEMBL10838798 | 0.81 | POLB (0.58) | MT-CO2KMT2AMEN1CXCR2PKN2 | |
| SCHEMBL4173936 | 0.81 | POLB (0.52) | MT-CO2KMT2AMEN1POLBSIRT2 | |
| SCHEMBL10838506 | 0.81 | HPGD (0.57) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL10838068 | 0.81 | L3MBTL1 (0.54) | MT-CO2KMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |