Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 4/20 | 0.83 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674998 | 0.91 | MT-CO2 (1.00) | MT-CO2CXCR2SIRT2KMT2AMEN1 | |
| SCHEMBL10980741 | 0.91 | MT-CO2 (0.89) | MT-CO2CXCR2SIRT2KMT2AMEN1 | |
| SCHEMBL5357441 | 0.90 | MT-CO2 (0.69) | MT-CO2CXCR2SIRT2KMT2AMEN1 | |
| SCHEMBL10985039 | 0.86 | MAPT (0.69) | MT-CO2KMT2AMEN1KDM4EHPGD | |
| SCHEMBL28689403 | 0.86 | MT-CO2 (0.72) | MT-CO2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL11901003 | 0.82 | KMT2A (0.89) | KMT2AGAAHPGDLMNAL3MBTL1 | |
| SCHEMBL31680569 | 0.82 | KMT2A (0.89) | KMT2AGAAHPGDLMNAL3MBTL1 | |
| SCHEMBL7199403 | 0.82 | MT-CO2 (0.63) | MT-CO2SIRT2 | |
| SCHEMBL11760920 | 0.82 | ALDH1A1 (0.62) | MT-CO2CXCR2SIRT2KMT2AMEN1 | |
| SCHEMBL13932577 | 0.82 | KDM4E (0.65) | MT-CO2KMT2AMEN1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |