Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332408 | 0.86 | MIF (0.65) | MIFGABRA1GABRB2TSHRTRPV1 | |
| SCHEMBL22444496 | 0.81 | GABRA1 (0.52) | MIFGABRA1GABRB2TSHRPOLB | |
| SCHEMBL8855753 | 0.76 | MIF (0.53) | MIFGABRA1GABRB2TRPV1TRPA1 | |
| SCHEMBL4199089 | 0.75 | GABRA1 (0.60) | GABRA1GABRB2TSHRPOLBTRPV1 | |
| SCHEMBL3890926 | 0.74 | MIF (0.52) | MIFHPGDCYP3A4CYP1A2HTR2B | |
| SCHEMBL3886974 | 0.74 | MIF (0.52) | MIFHPGDCYP3A4CYP1A2HTR2B | |
| SCHEMBL3886978 | 0.74 | MIF (0.52) | MIFHPGDCYP3A4CYP1A2HTR2B | |
| 1-Phenylethyl Isothiocyanate SCHEMBL3792824 | 0.71 | MIF (1.00) | MIFTSHRPOLBTRPV1TRPA1 | |
| 1-Phenylethyl Isothiocyanate SCHEMBL3795180 | 0.71 | MIF (1.00) | MIFTSHRPOLBTRPV1TRPA1 | |
| 1-Phenylethyl Isothiocyanate SCHEMBL156959 | 0.71 | MIF (1.00) | MIFTSHRPOLBTRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312326-B2 | Fluorescent labeled nucleotide derivatives | BECKMAN COULTER, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1732989-A1 | FLUORESCENT LABELED NUCLEOTIDE DERIVATIVES | Beckman Coulter, Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005103162-A1 | FLUORESCENT LABELED NUCLEOTIDE DERIVATIVES | BECKMAN COULTER, INC. (US) | 2005-11-03 | — | — | WO | disclosed |
| US-20050227240-A1 | Fluorescent labeled nucleotide derivatives | BECKMAN COULTER, INC. | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227240-A1 | Fluorescent labeled nucleotide derivatives | RNGTT, DNTT, POLRMT | MIF 4143/4885GABRA1 3914/4885GABRB2 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.