Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351732 | 0.96 | TSHR (0.65) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL3099156 | 0.86 | TSHR (0.62) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL27953228 | 0.81 | TSHR (0.88) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL14975 | 0.81 | TSHR (0.88) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Acetonitrile SCHEMBL4786430 | 0.79 | TSHR (0.75) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL5365497 | 0.79 | CYP1A2 (0.53) | TSHRALDH1A1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL444990 | 0.78 | TSHR (0.58) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Dimethyl Succinate SCHEMBL8829301 | 0.78 | TSHR (0.82) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL3502791 | 0.78 | TSHR (0.82) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL1286873 | 0.78 | TSHR (0.82) | TSHRLMNAALDH1A1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | EIGENBRODT ERICH | 2007-10-11 | — | — | US | disclosed |
| US-7223784-B2 | Compounds for the modulation of the glycolysis enzyme and/or transaminase complex | ScheBo® Biotech AG (DE) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | PC, GOT1, PCK1 | TSHR 3366/4885LMNA 2467/4885ALDH1A1 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.