Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948473 | 0.74 | SSTR4 (0.42) | — | |
| SCHEMBL5367875 | 0.70 | KMT2A (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL1662863 | 0.70 | SSTR4 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL27790028 | 0.69 | SLC6A2 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL28001409 | 0.69 | ALDH1A1 (0.40) | — | |
| SCHEMBL28212523 | 0.69 | ALDH1A1 (0.40) | — | |
| SCHEMBL4196853 | 0.66 | SLC6A2 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL6920953 | 0.64 | SLC6A3 (0.69) | — | |
| SCHEMBL2380649 | 0.64 | SLC6A2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL28915569 | 0.64 | SLC6A2 (0.53) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |