SCHEMBL5358732

SCHEMBL5358732

CCN(CC)c1[c]cccc1-c1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HSD17B10 Q99714 3/20 0.34
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
NPC1 O15118 1/20 0.33
RECQL P46063 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 2/20 0.32
PSMD14 O00487 1/20 0.32
MAPK1 P28482 1/20 0.32
GFER P55789 1/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060740 0.73 ALDH1A1 (0.52) ALDH1A1L3MBTL1HSD17B10CYP3A4SMN1; SMN2
SCHEMBL9297636 0.72 DDB1 (0.32) ALDH1A1L3MBTL1GAATDP1MAPK1
SCHEMBL7487017 0.71 PGR (0.39) ALDH1A1HSD17B10CYP3A4SMN1; SMN2ALOX15
SCHEMBL11129070 0.71 S100B (0.33) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2KDM4E
SCHEMBL6455528 0.71 AR (0.33) ALDH1A1L3MBTL1CYP3A4RECQLTDP1
SCHEMBL3373647 0.70 ALDH1A1 (0.59) ALDH1A1L3MBTL1HSD17B10CYP3A4SMN1; SMN2
SCHEMBL6711035 0.70 ALDH1A1 (0.32) ALDH1A1L3MBTL1CYP3A4GAARECQL
SCHEMBL2959668 0.69 SMN1; SMN2 (0.33) ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA
SCHEMBL2964345 0.69 MAPT (0.34) ALDH1A1CYP3A4SMN1; SMN2KDM4ENPC1
SCHEMBL6555858 0.69 ALDH1A1 (0.37) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007122341-A2 SPECIFIC MONOCATIONIC MONOCHROMOPHORIC HYDRAZONE COMPOUNDS CONTAINING A 2-(BENZ)IMIDAZOLIUM UNIT, THEIR SYNTHESIS, DYEING COMPOSITIONS COMPRISING THEM, METHOD OF DYEING KERATIN FIBRES L'ORÉAL (FR) 2007-11-01 WO claimed
WO-2007122341-A2 SPECIFIC MONOCATIONIC MONOCHROMOPHORIC HYDRAZONE COMPOUNDS CONTAINING A 2-(BENZ)IMIDAZOLIUM UNIT, THEIR SYNTHESIS, DYEING COMPOSITIONS COMPRISING THEM, METHOD OF DYEING KERATIN FIBRES L'ORÉAL (FR) 2007-11-01 WO disclosed