Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22796495 | 0.79 | TSHR (0.31) | TSHR | |
| SCHEMBL20320644 | 0.78 | TSHR (0.36) | TSHR | |
| SCHEMBL22418629 | 0.77 | ALDH1A1 (0.34) | TSHRTLR7 | |
| SCHEMBL4205888 | 0.74 | — | — | |
| SCHEMBL25659408 | 0.71 | TSHR (0.41) | TSHRTLR7 | |
| SCHEMBL917646 | 0.71 | TLR7 (0.35) | TSHRTLR7 | |
| SCHEMBL8960380 | 0.71 | TSHR (0.36) | TSHRTLR7 | |
| SCHEMBL27033804 | 0.68 | RXRA (0.38) | TSHRTLR7 | |
| SCHEMBL9009820 | 0.67 | TSHR (0.35) | TSHRTLR7 | |
| SCHEMBL10002246 | 0.66 | TSHR (0.37) | TSHRTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |