Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364006 | 0.87 | AR (0.52) | ARKMT2A | |
| SCHEMBL14347749 | 0.81 | AR (0.47) | AR | |
| SCHEMBL6466964 | 0.77 | AR (0.66) | AR | |
| SCHEMBL5368784 | 0.75 | AR (0.58) | ARGRIA2GRIA4 | |
| SCHEMBL6889299 | 0.74 | AR (0.72) | AR | |
| SCHEMBL5362254 | 0.74 | AR (0.60) | ARGRIA2GRIA4 | |
| SCHEMBL5362436 | 0.74 | CYP11B2 (0.40) | ARKMT2A | |
| SCHEMBL6469732 | 0.72 | AR (0.82) | ARKMT2A | |
| SCHEMBL14347768 | 0.72 | AR (0.57) | ARGRIA2GRIA4 | |
| SCHEMBL5361382 | 0.71 | AR (0.48) | ARGRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |