Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347749 | 0.84 | AR (0.47) | ARCYP11B2CHEK1CCNCCDK8 | |
| SCHEMBL14347768 | 0.84 | AR (0.57) | ARCYP11B2CCNCCDK8GRIA2 | |
| SCHEMBL5362232 | 0.80 | AR (0.61) | ARCYP11B2CCNCCDK8GRIA2 | |
| SCHEMBL14347772 | 0.78 | AR (0.53) | ARCYP11B2CCNCCDK8 | |
| SCHEMBL5365892 | 0.78 | AR (0.65) | ARCYP11B2CCNCCDK8CYP11B1 | |
| SCHEMBL6469428 | 0.78 | AR (0.58) | ARCYP11B2CCNCCDK8GRIA2 | |
| SCHEMBL5367267 | 0.78 | AR (0.52) | ARCYP11B2CCNCCDK8GRIA2 | |
| SCHEMBL5362254 | 0.78 | AR (0.60) | ARGRIA2GRIA4FNTAFNTB | |
| SCHEMBL6468889 | 0.77 | AR (0.86) | ARCYP11B2CCNCCDK8CYP11B1 | |
| SCHEMBL5361308 | 0.77 | CYP11B2 (0.41) | ARCYP11B2CCNCCDK8FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |