Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 4/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363055 | 0.87 | EGLN1 (0.51) | EGLN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL5351199 | 0.83 | EGLN1 (0.47) | EGLN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL5364912 | 0.81 | KMT2A (0.67) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL5367089 | 0.80 | GAA (0.62) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL5369173 | 0.79 | KMT2A (0.59) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL5397042 | 0.76 | KMT2A (0.58) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL5402536 | 0.76 | LMNA (0.55) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL3590806 | 0.75 | ADORA3 (0.69) | MAPTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL5412970 | 0.74 | PTGDR2 (0.62) | PPARGNCOA2NCOA1MAPTKMT2A | |
| SCHEMBL5413651 | 0.74 | PTGDR2 (0.63) | MAPTKMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |