Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359196 | 0.87 | EGLN1 (0.50) | EGLN1MAPTHDAC6HDAC3HDAC1 | |
| SCHEMBL5351199 | 0.84 | EGLN1 (0.47) | EGLN1MAPTHDAC6HDAC3HDAC1 | |
| SCHEMBL5360243 | 0.84 | HDAC6 (0.49) | MAPTHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL5354225 | 0.79 | MAPT (0.57) | MAPTKDM4ENPSR1SCDALDH1A1 | |
| SCHEMBL5365211 | 0.78 | CDC7 (0.55) | MAPTPTGS2NPSR1SCDALDH1A1 | |
| SCHEMBL3316055 | 0.75 | PTGS2 (0.59) | HDAC6HDAC1HDAC2HDAC8PTGS2 | |
| SCHEMBL5412989 | 0.73 | MAPT (0.51) | MAPTHDAC6HDAC1HDAC11KDM4E | |
| SCHEMBL6983554 | 0.72 | EGLN1 (0.76) | EGLN1MAPTNSD2HPGDMEN1 | |
| SCHEMBL4914715 | 0.72 | ALDH1A1 (0.48) | MAPTHDAC6KDRKDM4ENPSR1 | |
| SCHEMBL5392676 | 0.71 | MAPT (0.48) | MAPTHDAC6HDAC1HDAC11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |