SCHEMBL5359524

SCHEMBL5359524

Cl[Si](Cl)(Cl)c1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
ENPP1 P22413 2/20 0.37
HNF4A P41235 1/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
METAP2 P50579 1/20 0.35
TNF P01375 1/20 0.35
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
MAP4K4 O95819 1/20 0.34
CSF1R P07333 1/20 0.34
FGFR1 P11362 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12815312 0.88 CYP2A6 (0.41) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
SCHEMBL5927658 0.82 CYP2A6 (0.48) CYP2A6ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL7199355 0.79 FABP4 (0.44) CYP2A6ALDH1A1HPGDLMNAMAPT
SCHEMBL31175994 0.78 ALDH1A1 (0.37) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
SCHEMBL192418 0.77 ALDH1A1 (0.50) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
SCHEMBL31591138 0.76 ALDH1A1 (0.36) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
SCHEMBL28855471 0.75 ALDH1A1 (0.38) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
SCHEMBL9469764 0.74 ALDH1A1 (0.48) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
Water SCHEMBL432858 0.74 ALDH1A1 (0.48) CYP2A6ENPP1HNF4AALDH1A1HSD17B10
Ammonia Solution, Strong SCHEMBL21647364 0.74 ALDH1A1 (0.48) CYP2A6ENPP1HNF4AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7230335-B2 Inspection methods and structures for visualizing and/or detecting specific chip structures INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-06-12 US disclosed
US-20060234151-A1 Functional organic thin film, organic thin-film transistor, and methods for producing these SHARP KABUSHIKI KAISHA (JP) 2006-10-19 US disclosed
US-20060231827-A1 Functional organic thin film, organic thin-film transistor, pi-electron conjugated molecule-containing silicon compound, and methods of forming them SHARP KABUSHIKI KAISHA (JP) 2006-10-19 US disclosed
US-20060071208-A1 INSPECTION METHODS AND STRUCTURES FOR VISUALIZING AND/OR DETECTING SPECIFIC CHIP STRUCTURES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-04-06 US disclosed
EP-1598387-A1 FUNCTIONAL ORGANIC THIN FILM, ORGANIC THIN-FILM TRANSISTOR, PI-ELECTRON CONJUGATED MOLECULE-CONTAINING SILICON COMPOUND, AND METHODS OF FORMING THEM Sharp Kabushiki Kaisha (JP) 2005-11-23 EP disclosed