Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361928 | 0.92 | AR (0.49) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL5360596 | 0.90 | AR (0.47) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL14347608 | 0.89 | ALDH1A1 (0.51) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL4921544 | 0.87 | RAB9A (0.46) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL6466270 | 0.85 | AR (0.63) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL6466360 | 0.85 | RAB9A (0.57) | LMNAALDH1A1NPSR1HTTKMT2A | |
| SCHEMBL6464844 | 0.81 | HTT (0.53) | ALDH1A1NPSR1HTTRXFP1KMT2A | |
| SCHEMBL5354675 | 0.81 | AR (0.47) | ALDH1A1NPSR1HTTRXFP1KMT2A | |
| SCHEMBL6464539 | 0.80 | ALDH1A1 (0.58) | LMNAALDH1A1NPSR1HTTRXFP1 | |
| SCHEMBL6465908 | 0.80 | ALDH1A1 (0.71) | LMNAALDH1A1NPSR1HTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |