Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13362172 | 0.90 | CYP11B2 (0.39) | ARCYP11B2RIPK3SLC22A12KDM1A | |
| SCHEMBL5487110 | 0.81 | KMT2A (0.40) | ARCYP11B2FNTAFNTB | |
| SCHEMBL5364131 | 0.78 | CYP11B2 (0.40) | ARCYP11B2RIPK3KDM1A | |
| SCHEMBL13335446 | 0.73 | AR (0.34) | AR | |
| SCHEMBL5366156 | 0.73 | AR (0.37) | ARCYP11B2CYP11B1 | |
| SCHEMBL5357688 | 0.69 | CYP11B2 (0.36) | ARCYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL5353839 | 0.68 | KMT2A (0.39) | ARCYP11B2CYP11B1 | |
| SCHEMBL5365214 | 0.68 | CYP11B2 (0.43) | ARCYP11B2CYP11B1 | |
| SCHEMBL5361462 | 0.66 | CYP11B2 (0.41) | ARCYP11B2CYP11B1KDM1A | |
| SCHEMBL4919245 | 0.66 | AR (0.69) | ARCYP11B2CYP11B1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |