Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357164 | 0.89 | CYP11B2 (0.39) | ARCYP11B2PTGDR2GYS1CCNC | |
| SCHEMBL5362074 | 0.84 | CYP11B2 (0.35) | ARCYP11B2PTGDR2GYS1CCNC | |
| SCHEMBL5357234 | 0.84 | CYP11B2 (0.37) | ARCYP11B2PTGDR2GYS1CCNC | |
| SCHEMBL5353540 | 0.81 | CYP11B2 (0.38) | ARCYP11B2PTGDR2GYS1CCNC | |
| SCHEMBL5367787 | 0.78 | CYP11B2 (0.35) | CYP11B2PTGDR2GYS1CCNCCDK8 | |
| SCHEMBL5354656 | 0.75 | AR (0.40) | ARCYP11B2CCNCCDK8 | |
| SCHEMBL5355359 | 0.74 | CYP11B2 (0.37) | ARCYP11B2NSD2CYP11B1 | |
| SCHEMBL5359725 | 0.74 | AR (0.48) | ARPTGDR2GYS1SDHB | |
| SCHEMBL5358762 | 0.73 | CYP11B2 (0.40) | ARCYP11B2CCNCCDK8 | |
| SCHEMBL5359996 | 0.73 | AR (0.39) | ARCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |