Sugi Predict

Sugi Predict / Compounds / SCHEMBL536001

SCHEMBL536001

SCHEMBL536001

CS(=O)(=O)c1ccccc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ BLM P54132 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ ALDH1A1 P00352 4/20 0.48
▸ TSHR P16473 2/20 0.48
▸ TRIM24 O15164 1/20 0.43
▸ TRIM33 Q9UPN9 1/20 0.43
▸ CYP2C9 P11712 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ HTT P42858 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ BRD4 O60885 1/20 0.38
▸ CREBBP Q92793 1/20 0.38
▸ BCAT2 O15382 1/20 0.38
▸ GAA P10253 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21662118 0.84 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL19127445 0.84 MEN1 (0.44) LMNAKMT2AMEN1THRBBLM
SCHEMBL27960209 0.83 ALDH1A1 (0.45) LMNAKMT2AMEN1THRBBLM
SCHEMBL12345362 0.80 BRD4 (0.38) LMNAKMT2AMEN1THRBBLM
SCHEMBL9567510 0.80 ALDH1A1 (0.41) LMNAKMT2AMEN1THRBBLM
SCHEMBL29196725 0.79 MEN1 (0.39) LMNAKMT2AMEN1THRBBLM
SCHEMBL5252641 0.79 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL16495208 0.78 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL17680988 0.78 BRD4 (0.43) LMNAKMT2AMEN1THRBBLM
SCHEMBL5088711 0.77 MEN1 (0.52) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118853641-A L-threonine aldolase and preparation method and application thereof 弈柯莱生物科技(重庆)有限公司 2024-10-29 — — CN claimed
CN-118164878-B Preparation method of p-methylsulfonyl benzaldehyde 山东德澳精细化学品有限公司 2024-07-26 — — CN claimed
CN-117658872-A Synthesis process of 1, 3-dihydroxy-1-p-methylsulfonyl propiophenone 山东普洛汉兴医药有限公司 2024-03-08 — — CN claimed
CN-117126897-A Method for preparing (2S, 3R) -p-methylsulfonyl phenylserine ethyl ester 弈柯莱生物科技(集团)股份有限公司 2023-11-28 — — CN claimed
CN-116375615-A Preparation method of florfenicol amine, intermediate thereof and preparation method thereof 弈柯莱生物科技(上海)股份有限公司 2023-07-04 — — CN claimed
CN-113481188-B Threonine aldolase mutant and application thereof in preparation of substituted phenylserine derivative 王喆明 2023-03-24 — — CN claimed
CN-115677546-B Chiral synthesis method of D-p-methylsulfonylphenylserine ethyl ester 山东国邦药业有限公司 2023-03-07 — — CN claimed
CN-115677546-A Chiral synthesis method of D-p-methylsulfonylphenylserine ethyl ester 山东国邦药业有限公司 2023-02-03 — — CN claimed
CN-113322289-B Process for preparing (2R,3S) -2-amino-3-hydroxy-3- (4- (methylsulfonyl) phenyl) propionic acid 天津工微生物科技有限公司 2021-10-08 — — CN claimed
CN-113481188-A Threonine aldolase mutant and application thereof in preparation of substituted phenylserine derivative 王喆明 2021-10-08 — — CN claimed
EP-3630795-A1 ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) 2020-04-08 — — EP claimed
US-20200068880-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE AMVAC CHEMICAL CORPORATION 2020-03-05 — — US claimed
US-20190239504-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE AMVAC CHEMICAL CORPORATION 2019-08-08 — — US claimed
US-20190000076-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE AMVAC CHEMICAL CORPORATION 2019-01-03 — — US claimed
WO-2018219108-A1 ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) 2018-12-06 — — WO claimed
CN-106966932-A A kind of preparation method to MSM benzaldehyde 福建铭医药科技有限公司 2017-07-21 — — CN claimed
CN-103819371-B A kind of synthetic method to methylsulfonyl benzaldehyde DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2016-05-04 — — CN claimed
US-20140031232-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE AMVAC CHEMICAL CORPORATION (US) 2014-01-30 — — US claimed
WO-2014018775-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE AMVAC CHEMICAL CORPORATION (US) 2014-01-30 — — WO claimed
EP-1718605-B1 PROCESSES FOR THE PREPARATION OF ARYL-AND HETEROARYL-ALKYLSULFONYL HALIDES WYETH CORP (US) 2009-06-17 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190239504-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE DDT, HDHD5, GMDS LMNA 4396/4885KMT2A 1164/4885MEN1 4577/4885
US-20190000076-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE DDT, HDHD5, GMDS LMNA 4396/4885KMT2A 1164/4885MEN1 4577/4885
US-20200068880-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE DDT, HDHD5, GMDS LMNA 4396/4885KMT2A 1164/4885MEN1 4577/4885
US-20140031232-A1 DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE DDT, HDHD5, GMDS LMNA 4396/4885KMT2A 1164/4885MEN1 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.