SCHEMBL5360259

SCHEMBL5360259

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)OOCC(O)CO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.60
DGKA P23743 1/20 0.59
ALDH1A1 P00352 5/20 0.57
CYP3A4 P08684 2/20 0.57
ALOX15 P16050 2/20 0.57
HSD17B10 Q99714 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
TSHR P16473 1/20 0.57
MAPT P10636 3/20 0.51
F7 P08709 2/20 0.51
F3 P13726 2/20 0.51
CYP19A1 P11511 2/20 0.51
NR1I2 O75469 2/20 0.51
PTGS2 P35354 2/20 0.51
HPGD P15428 2/20 0.51
OXER1 Q8TDS5 1/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
FFAR1 O14842 1/20 0.51
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5918084 0.92 FAAH (0.70) FAAHDGKAALDH1A1MAPTHPGD
SCHEMBL3848771 0.88 FAAH (0.76) FAAHDGKAALDH1A1MAPTHPGD
SCHEMBL7729906 0.88 DGKA (0.75) FAAHDGKAKDM4EMEN1LMNA
SCHEMBL3909257 0.88 DGKA (0.75) FAAHDGKAKDM4EMEN1LMNA
1-Monolinolenin SCHEMBL23611226 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15
1-Monolinolenin SCHEMBL1580284 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15
1-Monolinolenin SCHEMBL18340460 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15
SCHEMBL13623309 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15
1-Monolinolenin SCHEMBL23611225 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15
SCHEMBL9905950 0.87 FAAH (0.78) FAAHDGKAALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060252708-A1 Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders SHENZHEN CHIPSCREEN BIOSCIENCES, LTD. (GN) 2006-11-09 US claimed
JP-2007269683-A SKIN PREPARATION FOR EXTERNAL USE KOSE CORP 2007-10-18 JP disclosed
US-20060252708-A1 Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders SHENZHEN CHIPSCREEN BIOSCIENCES, LTD. (GN) 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252708-A1 Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders FASN, RFT1, FFAR1 FAAH 533/4885DGKA 2561/4885ALDH1A1 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.