SCHEMBL7729906

SCHEMBL7729906

CCCCCCCC/C=C\CCCCCCCC(=O)OOCC(O)CO

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.75
FAAH O00519 2/20 0.64
KDM4E B2RXH2 1/20 0.60
DUSP3 P51452 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
LMNA P02545 1/20 0.60
PRKCA P17252 2/20 0.56
PRKCE Q02156 1/20 0.56
PRKCQ Q04759 1/20 0.56
PRKCD Q05655 1/20 0.56
LPAR1 Q92633 5/20 0.53
ENPP2 Q13822 2/20 0.53
LPAR4 Q99677 2/20 0.53
LPAR5 Q9H1C0 2/20 0.53
LPAR2 Q9HBW0 2/20 0.53
LPAR3 Q9UBY5 2/20 0.53
CES2 O00748 1/20 0.53
LPAR6 P43657 1/20 0.53
TRPV1 Q8NER1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3909257 1.00 DGKA (0.75) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL5918084 0.96 FAAH (0.70) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL3848771 0.92 FAAH (0.76) DGKAFAAHSELP
SCHEMBL5174457 0.92 DGKA (0.64) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL5936305 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL9179173 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL1232546 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL7655873 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL4198660 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1
SCHEMBL333190 0.91 LMNA (0.71) DGKAFAAHKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111888475-A Sustained-release preparation, preparation method and application thereof in preparing in-situ tumor immune combined treatment medicine 华中科技大学 2020-11-06 CN claimed
CN-111888475-B Sustained-release preparation, preparation method and application thereof in preparing in-situ tumor immune combined treatment medicine 华中科技大学 2022-01-07 CN disclosed
CN-111888475-A Sustained-release preparation, preparation method and application thereof in preparing in-situ tumor immune combined treatment medicine 华中科技大学 2020-11-06 CN disclosed
US-6403122-B1 BIOAVAILABILITY BASED ON A LIPOLYTIC INDIFFERENT VEHICLE, AN ABSORPTION PROMOTER AND ACTIVE N-METHYLATED CYCLIC UNDECAPEPTIDES OR MACROLIDE LACTONES; SELF ASSEMBLY DRUG DELIVERY SYSTEM (SADDS); CYCLOSPORINS GALENA AS (CZ) 2002-06-11 US disclosed
EP-0670751-B1 IMPROVED SENSOR MEMBRANES AU MEMBRANE & BIOTECH RES INST (AU) 2001-12-12 EP disclosed
EP-1130386-A1 Improved sensor membranes AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2001-09-05 EP disclosed
EP-1130387-A1 Linker lipid for sensor membranes AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2001-09-05 EP disclosed
EP-1130388-A1 Improved sensor membranes AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2001-09-05 EP disclosed
EP-1104883-A2 Improved sensor membranes AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2001-06-06 EP disclosed
US-6221395-B1 POORLY SOLUBLE IN WATER ACTIVE PRINCIPLE (ES: NIFEDIPINE) IS TREATED WITH A SODIUM LAURYL SULFATE SURFACTANT AND HYDROXYPROPYL METHYL CELLULOSE; HIGH BIOAVAILABILITY JAGOTEC AG (CH) 2001-04-24 US disclosed
US-5798030-A FOR DETECTING ANALYTE IN SAMPLE; ELECTRODE AND BILAYER MEMBRANE, THE CONDUCTANCE OF THE MEMBRANE BEING DEPENDENT ON THE PRESENCE OF THE ANALYTE AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1998-08-25 US disclosed
US-5783054-A CONTACTING ELECTRODE WITH LINKER LIPID FOR USE IN ATTACHING MEMBRANE CONTAINING IONOPHORE TO ELECTRODE AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1998-07-21 US disclosed
US-5753093-A USING A LINKER LIPID FOR ATTACHING A MEMBRANE INCLUDING A PLURALITY OF IONOPHORES TO AN ELECTRODE; PROVIDING A SPACE BETWEEN THE MEMBRANE AND THE ELECTRODE AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1998-05-19 US disclosed
US-5741409-A BIOSENSORS, ION SELECTIVE ELECTRODES AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1998-04-21 US disclosed
US-5637201-A LINKER LIPID FOR USE IN ATTACHING A MEMBRANE, COMPRISES WITH IN THE SAME MOLECULE HYDROPHILIC AND HYDROPHOBIC REGIONS AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INS. 1997-06-10 US disclosed
EP-0670751-A4 IMPROVED SENSOR MEMBRANES. AU MEMBRANE & BIOTECH RES INST (AU) 1996-09-25 EP disclosed
EP-0670751-A1 IMPROVED SENSOR MEMBRANES AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1995-09-13 EP disclosed
WO-1994007593-A1 IMPROVED SENSOR MEMBRANES AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1994-04-14 WO disclosed