Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204796 | 0.76 | CLCN2 (0.38) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL11309654 | 0.74 | MAPT (0.46) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL9358199 | 0.73 | MEN1 (0.54) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL30678386 | 0.73 | MEN1 (0.60) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL78525 | 0.73 | MEN1 (0.60) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL29366166 | 0.73 | MEN1 (0.60) | MEN1KMT2ANSD2POLBBLM | |
| Ether SCHEMBL28753717 | 0.71 | MAPT (0.59) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL11131632 | 0.70 | POLB (0.63) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL29940221 | 0.70 | POLB (0.63) | MEN1KMT2ANSD2POLBBLM | |
| SCHEMBL55230 | 0.70 | MAPT (0.74) | MEN1KMT2ANSD2POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | disclosed |
| US-7211117-B2 | Composition for dyeing keratin fibers comprising at least one dye chosen from monoheteroyldiarylmethane direct dyes and the leuco precursors thereof and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | disclosed |
| EP-1621184-A1 | Hair dyeing composition comprising an elastomeric film-forming polymer and a dyeing material | L'OREAL (FR) | 2006-02-01 | — | — | EP | disclosed |
| US-20040216247-A1 | Composition for dyeing keratin fibers comprising at least one dye chosen from monoheteroyldiarylmethane direct dyes and the leuco precursors thereof and dyeing method using it | L'OREAL S.A. (FR) | 2004-11-04 | — | — | US | disclosed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | KRT18, KMO, KRTCAP2 | MEN1 4090/4885KMT2A 382/4885NSD2 919/4885 |
| US-20040216247-A1 | Composition for dyeing keratin fibers comprising at least one dye chosen from monoheteroyldiarylmethane direct dyes and the leuco precursors thereof and dyeing method using it | KRT18, KMO, PLOD3 | MEN1 4140/4885KMT2A 490/4885NSD2 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.