SCHEMBL5360904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8345602	0.84	KEAP1 (0.47)	HPGDHSD17B10CYP1A2CYP3A4CYP2C19
	SCHEMBL10479354	0.83	KDM4E (0.56)	HPGDHSD17B10CYP1A2CYP3A4CYP2C19
	SCHEMBL6647138	0.83	TP53 (0.55)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL8688316	0.81	TP53 (0.50)	HPGDHSD17B10CYP1A2CYP3A4CYP2C19
	SCHEMBL1097237	0.80	TP53 (0.52)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL29822323	0.78	TP53 (0.69)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL610480	0.78	TP53 (0.69)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL7287054	0.78	HCRTR1 (0.60)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL4155173	0.78	TP53 (0.50)	HPGDKEAP1TP53TSHRMAPK1
	SCHEMBL6772801	0.78	TP53 (0.50)	HPGDKEAP1TP53TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.