Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360904 | 0.84 | HPGD (0.57) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL6647138 | 0.83 | TP53 (0.55) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL1097237 | 0.80 | TP53 (0.52) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL29822323 | 0.78 | TP53 (0.69) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL610480 | 0.78 | TP53 (0.69) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL4155173 | 0.78 | TP53 (0.50) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL6772801 | 0.78 | TP53 (0.50) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL7287054 | 0.78 | HCRTR1 (0.60) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL8688316 | 0.78 | TP53 (0.50) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL14919390 | 0.77 | KEAP1 (0.49) | KEAP1TP53TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |