Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKG1 | Q13976 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536095 | 0.92 | BRD4 (0.35) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL410352 | 0.87 | GFER (0.42) | PRKG1BRD4BRPF1POLBHPGD | |
| SCHEMBL536674 | 0.87 | S1PR1 (0.39) | POLBTSHRNR1I2SMARCA2SMARCA4 | |
| SCHEMBL534781 | 0.86 | S1PR1 (0.40) | NR1H4 | |
| SCHEMBL408083 | 0.84 | GFER (0.46) | POLBPLAURHPGDKDM4EGAA | |
| SCHEMBL406660 | 0.82 | NR4A2 (0.46) | NPC1RAB9APOLBTSHRHPGD | |
| SCHEMBL1479064 | 0.75 | GFER (0.46) | POLBTSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL26219182 | 0.73 | NR4A2 (0.46) | NPC1RAB9APOLBTSHRHPGD | |
| SCHEMBL406852 | 0.72 | TTR (0.45) | RAB9APOLBTSHRHPGDKDM4E | |
| SCHEMBL406995 | 0.72 | S1PR1 (0.49) | NPC1RAB9APOLBTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112461-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-07 | — | — | WO | disclosed |