Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536094 | 0.92 | PRKG1 (0.38) | BRD4BRPF1NR1I2SMARCA2SMARCA4 | |
| SCHEMBL534781 | 0.79 | S1PR1 (0.40) | — | |
| SCHEMBL536674 | 0.79 | S1PR1 (0.39) | NR1I2SMARCA2SMARCA4PBRM1NR1H2 | |
| SCHEMBL410352 | 0.78 | GFER (0.42) | BRD4BRPF1HPGDALOX15HSD17B10 | |
| SCHEMBL406399 | 0.75 | MAPK14 (0.44) | HSD17B10NPC1RAB9AMAPK14ALDH1A1 | |
| SCHEMBL408083 | 0.75 | GFER (0.46) | HPGDHSD17B10KDM4EGAAGFER | |
| SCHEMBL536178 | 0.72 | S1PR1 (0.39) | NR1I2SMARCA2SMARCA4PBRM1NR1H2 | |
| SCHEMBL406660 | 0.72 | NR4A2 (0.46) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL407058 | 0.69 | AR (0.39) | NR1I2SMARCA2SMARCA4PBRM1NR1H2 | |
| SCHEMBL410064 | 0.66 | PDK2 (0.45) | HPGDHSD17B10NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112461-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-07 | — | — | WO | disclosed |