Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472669 | 0.94 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2KCNH2KDM4E | |
| SCHEMBL29816321 | 0.94 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2KCNH2KDM4E | |
| SCHEMBL28490104 | 0.90 | KDM4E (0.53) | SLC6A4SLC6A3SLC6A2KDM4EKMT2A | |
| SCHEMBL11835632 | 0.86 | ESR1 (0.50) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL33719724 | 0.84 | ALDH1A1 (0.45) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL18910944 | 0.81 | CYP2A6 (0.46) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL2272581 | 0.81 | DRD2 (0.53) | SLC6A4SLC6A3SLC6A2KDM4EKMT2A | |
| SCHEMBL5585284 | 0.81 | KDM4E (0.47) | SLC6A4SLC6A3SLC6A2KDM4EKMT2A | |
| SCHEMBL18905264 | 0.81 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2KCNH2KDM4E | |
| SCHEMBL18905296 | 0.79 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |