SCHEMBL18905296

SCHEMBL18905296

OC1(c2ccc3cc([SiH3])ccc3c2)CCCC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 11/20 0.37
SLC6A3 Q01959 11/20 0.37
SLC6A2 P23975 6/20 0.37
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
KCNH2 Q12809 2/20 0.33
ACSS2 Q9NR19 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905264 0.98 SLC6A4 (0.39) SLC6A4SLC6A3SLC6A2KDM4EKMT2A
SCHEMBL18905272 0.80 DRD2 (0.41) HRH3
SCHEMBL5361306 0.79 SLC6A4 (0.57) SLC6A4SLC6A3SLC6A2KDM4EKMT2A
SCHEMBL18905284 0.78 HRH3 (0.42) KMT2AHRH3
SCHEMBL12722306 0.78 CYP2A6 (0.48) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL18905451 0.77 OPRM1 (0.36) SLC6A4SLC6A2KMT2A
SCHEMBL29816321 0.77 SLC6A4 (0.50) SLC6A4SLC6A3SLC6A2KDM4EKMT2A
SCHEMBL11472669 0.77 SLC6A4 (0.50) SLC6A4SLC6A3SLC6A2KDM4EKMT2A
SCHEMBL18910944 0.76 CYP2A6 (0.46) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL18905270 0.76 OPRM1 (0.36) SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170154766-A1 SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-01 US disclosed