Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444164 | 0.85 | LMNA (0.57) | ALOX15HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5351076 | 0.81 | ALOX15 (0.57) | ALOX15HPGDALDH1A1SMN1; SMN2APEX1 | |
| SCHEMBL12131387 | 0.79 | FFAR1 (0.51) | ALOX15HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5717697 | 0.78 | GAA (0.66) | ALOX15HPGDALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14444295 | 0.77 | CYP1A2 (0.57) | ALOX15HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14444304 | 0.75 | L3MBTL1 (0.52) | ALOX15HPGDALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL11752836 | 0.74 | LMNA (0.56) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14444509 | 0.73 | CYP1A2 (0.56) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14444503 | 0.73 | CYP1A2 (0.54) | ALOX15HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL759274 | 0.72 | ALOX15 (1.00) | ALOX15ALDH1A1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | PNPO, P2RX6, P2RX1 | ALOX15 2980/4885HPGD 1714/4885ALDH1A1 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.