Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423807 | 0.75 | ALDH1A1 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL23430419 | 0.75 | ALDH1A1 (0.37) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3547581 | 0.71 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9693375 | 0.71 | KDM4E (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL6005148 | 0.71 | KDM4E (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28020567 | 0.71 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15174742 | 0.71 | KDM4E (0.45) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7450281 | 0.71 | KDM4E (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL27740696 | 0.71 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL5349811 | 0.69 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614819-A | REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-30 | — | — | US | claimed |
| US-4163669-A | CONTAINING HEAVY METAL SALT OF ORGANIC COMPOUND | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-08-07 | — | — | US | claimed |
| EP-4214200-A1 | LANCL LIGANDS | Nimmune Biopharma, Inc. (US) | 2023-07-26 | — | — | EP | disclosed |
| CN-113748109-B | Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands | 朗多生物制药股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116368133-A | NLRX1 ligand | 朗多生物制药股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20230167083-A1 | LANCL LIGANDS | LANDOS BIOPHARMA, INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-11459310-B2 | LANCL ligands | LANDOS BIOPHARMA, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| WO-2022087146-A1 | LANCL LIGANDS | LANDOS BIOPHARMA, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20220127250-A1 | LANCL LIGANDS | LANDOS BIOPHARMA, INC. (US) | 2022-04-28 | — | — | US | disclosed |
| CN-113748109-A | Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands | 朗多生物制药股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-0014494-B1 | PHOTOGRAPHIC IMAGING PROCESS AND MATERIALS SUITABLE THEREFOR | AGFA-GEVAERT N.V. (BE) | 1982-05-12 | — | — | EP | disclosed |
| US-4269923-A | Photographic imaging process and materials suitable therefor | AGFA-GEVAERT N.V. (BE) | 1981-05-26 | — | — | US | disclosed |
| US-4163669-A | CONTAINING HEAVY METAL SALT OF ORGANIC COMPOUND | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-08-07 | — | — | US | disclosed |
| US-4075021-A | COMPOUND WHICH RELEASES A SUBSTANCE WHICH PROMOTES BLEACHING OF DEVELOPED SILVER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1978-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127250-A1 | LANCL LIGANDS | LANCL2, LANCL1, LCLAT1 | KDM4E 3554/4885MEN1 473/4885ALDH1A1 4156/4885 |
| US-11459310-B2 | LANCL ligands | LANCL2, LANCL1, ACSL1 | KDM4E 3796/4885MEN1 364/4885ALDH1A1 3541/4885 |
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | KDM4E 855/4885MEN1 3783/4885ALDH1A1 1391/4885 |
| US-20230167083-A1 | LANCL LIGANDS | LANCL2, LANCL1, LCLAT1 | KDM4E 3554/4885MEN1 473/4885ALDH1A1 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.