Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536223 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19IDH1 | |
| SCHEMBL7118374 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP2C19IDH1 | |
| SCHEMBL8084333 | 0.71 | KCNH2 (0.34) | ALDH1A1LMNA | |
| SCHEMBL27571897 | 0.71 | HTT (0.34) | ALDH1A1 | |
| SCHEMBL14954643 | 0.71 | NR1H2 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14764818 | 0.70 | ADH1B (0.33) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL723613 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDCYP2C19IDH1 | |
| SCHEMBL1566053 | 0.66 | ALDH1A1 (0.34) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL296966 | 0.65 | ALDH1A1 (0.36) | ALDH1A1HPGDCYP2C19IDH1 | |
| SCHEMBL9559606 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617286-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9556205-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| EP-2576571-B1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-2782920-B1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| EP-2782920-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013075817-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| EP-2576571-A2 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20130065855-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-14 | — | — | US | disclosed |
| WO-2011151368-A2 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065855-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | TET3, TET1, PFAS | ADH1B 4405/4885ADH1C 3404/4885ADH1A 4258/4885 |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | TET3, TET1, PFAS | ADH1B 4405/4885ADH1C 3404/4885ADH1A 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.