SCHEMBL536229

SCHEMBL536229

OC(F)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
CYP3A4 P08684 4/20 0.41
GAA P10253 1/20 0.40
CNR2 P34972 1/20 0.39
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2C9 P11712 1/20 0.36
ACHE P22303 1/20 0.36
CYP2D6 P10635 2/20 0.36
SLC6A2 P23975 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11602791 0.83 CES2 (0.54) CES2CES1IDO1TDO2CYP3A4
SCHEMBL1902230 0.81 CES2 (0.52) CES2CES1IDO1TDO2CYP3A4
SCHEMBL30057873 0.81 CES2 (0.52) CES2CES1IDO1TDO2CYP3A4
SCHEMBL23489601 0.80 CES2 (0.47) CES2CES1IDO1TDO2CYP3A4
SCHEMBL23489602 0.80 CES2 (0.47) CES2CES1IDO1TDO2CYP3A4
SCHEMBL7777116 0.80 CES2 (0.53) CES2CES1IDO1TDO2CYP3A4
SCHEMBL29768740 0.78 IDO1 (0.43) CES2CES1IDO1TDO2CYP3A4
SCHEMBL1999868 0.78 IDO1 (0.43) CES2CES1IDO1TDO2CYP3A4
SCHEMBL213828 0.77 CES2 (0.48) CES2CES1IDO1TDO2CYP3A4
SCHEMBL625219 0.77 CES2 (0.48) CES2CES1IDO1TDO2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-211436624-U Centrifugal machine for difluorobenzyl alcohol production 江西犇牛医药化工有限公司 2020-09-08 CN claimed
CN-211371756-U PH meter is used in difluorobenzyl alcohol production laboratory 江西犇牛医药化工有限公司 2020-08-28 CN claimed
CN-211086157-U Melting point instrument for preparing difluorobenzyl alcohol compound 江西犇牛医药化工有限公司 2020-07-24 CN claimed
CN-111303179-A Synthesis of norcantharidin carboxylic acid difluoro benzyl ester and anti-tumor application thereof 遵义医科大学 2020-06-19 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-6967236-B1 Methods of processing and synthesizing electrically conductive polymers and precursors thereof to form electrically conductive polymers having high electrical conductivity INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-11-22 US claimed
EP-3882235-B1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND UNIV KOBE NAT UNIV CORP (JP) 2025-01-22 EP disclosed
US-12060312-B2 Production method for isocyanate compound NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2024-08-13 US disclosed
CN-111303179-B Synthesis of norcantharidin carboxylic acid difluoro benzyl ester and anti-tumor application thereof 遵义医科大学 2022-12-02 CN disclosed
CN-114835563-A Synthetic method of 4,4' -difluorobenzophenone 浙江中欣氟材股份有限公司 2022-08-02 CN disclosed
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2022-01-06 US disclosed
EP-3882235-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND National University Corporation Kobe University (JP) 2021-09-22 EP disclosed
CN-113038942-A Composition for treating fibrotic diseases containing benzhydrylthioacetamide (Benzhydryl ttoacetamide) compound as active ingredient 细胞离子生物医学株式会社 2021-06-25 CN disclosed
CN-1630645-A 5-HT receptor ligands and uses thereof PFIZER (US) 2005-06-22 CN disclosed
US-5837162-A CYCLIC ETHERS FOR LIQUID CRYSTAL DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-11-17 US disclosed
US-5626793-A Liquid-crystalline compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-05-06 US disclosed
WO-1993003113-A1 LIQUID-CRYSTAL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1993-02-18 WO disclosed
EP-0525140-A1 LIQUID-CRYSTAL COMPOUNDS MERCK PATENT GmbH (DE) 1993-02-03 EP disclosed
WO-1992013928-A1 LIQUID-CRYSTAL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1992-08-20 WO disclosed
EP-0373531-A1 Novel pyridobenzoxazine derivative WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1990-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060312-B2 Production method for isocyanate compound IDH2, CBR3, IDH3A CES2 1339/4885CES1 2811/4885IDO1 83/4885
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND IDH2, CBR3, IDH3A CES2 1339/4885CES1 2811/4885IDO1 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.