Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281731 | 0.77 | CTRC (0.39) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL15657030 | 0.72 | KMT2A (0.52) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL1828312 | 0.70 | KMT2A (0.41) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL11443179 | 0.67 | BRD4 (0.43) | KMT2AGAAMAPTALDH1A1HPGD | |
| SCHEMBL7268376 | 0.67 | KMT2A (0.45) | TSHRKMT2AGAAMAPTDDB1 | |
| SCHEMBL30978704 | 0.67 | KMT2A (0.39) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL1829741 | 0.67 | DDB1 (0.43) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL1828656 | 0.64 | TP53 (0.42) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL17898477 | 0.64 | MAPT (0.57) | CFTRGOPCTSHRKMT2AGAA | |
| SCHEMBL4083602 | 0.64 | CFTR (0.53) | CFTRGOPCTSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002443-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2004-01-01 | — | — | US | claimed |
| WO-2003008932-A2 | SIZE ENHANCED HEMOGLOBINS: SURFACE DECORATION AND CROSSLINKING OF THE PROTEIN WITH POLYOXY AKYLENE GLYCOLS | ALBERT EINSTEIN COLLEGE OF MEDECINE OF YESHIVA UNIVERSITY (US) | 2003-01-30 | — | — | WO | claimed |
| US-6017943-A | INTRAMOLECULARLY CROSSLINKING HEMOGLOBIN TO FORM A SYNTHETIC BLOOD | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-01-25 | — | — | US | claimed |
| US-5585484-A | USING ETHOXYLATED PHENYLMALEIMIDO COMPOUNDS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) | 1996-12-17 | — | — | US | claimed |
| EP-0254627-B1 | DERIVATIVES OF BENZHYDRYLOXYETHYLPIPERAZINE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1992-06-17 | — | — | EP | claimed |
| US-7169900-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169900-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20060111275-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ACHARYA SEETHARAMA A | 2006-05-25 | — | — | US | disclosed |
| US-20060111275-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ACHARYA SEETHARAMA A | 2006-05-25 | — | — | US | disclosed |
| US-7019117-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-03-28 | — | — | US | disclosed |
| US-7019117-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040002443-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2004-01-01 | — | — | US | disclosed |
| US-5770573-A | CS-1 peptidomimetics, compositions and methods of using the same | CYTEL CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |
| US-5750725-A | USING A SUBSTITUTED POLYETHERS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA (US) | 1998-05-12 | — | — | US | disclosed |
| US-5688913-A | OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS | CYTEL CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5585484-A | USING ETHOXYLATED PHENYLMALEIMIDO COMPOUNDS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| US-4908365-A | Pharmaceuticals | SOCIETE ANONYME (FR) | 1990-03-13 | — | — | US | disclosed |
| EP-0254627-A1 | Derivatives of benzhydryloxyethylpiperazine, processes for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-01-27 | — | — | EP | disclosed |