Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362473 | 0.77 | CFTR (0.43) | CTRCKMT2ADDB1CRBNCFTR | |
| SCHEMBL4773686 | 0.74 | ACHE (0.48) | KMT2ATSHRCYP19A1MEN1CYP2D6 | |
| SCHEMBL2345374 | 0.68 | ACHE (0.55) | SIGMAR1CYP19A1MAPTCYP3A4HTR2B | |
| SCHEMBL30785363 | 0.68 | ACHE (0.55) | SIGMAR1CYP19A1MAPTCYP3A4HTR2B | |
| SCHEMBL15657030 | 0.67 | KMT2A (0.52) | CTRCKMT2ADDB1CRBNCFTR | |
| SCHEMBL11881965 | 0.66 | SIGMAR1 (0.66) | KMT2ASIGMAR1MEN1CYP3A4CYP2D6 | |
| SCHEMBL1828312 | 0.65 | KMT2A (0.41) | CTRCKMT2ADDB1CRBNCFTR | |
| SCHEMBL5668502 | 0.64 | DDB1 (0.50) | KMT2ADDB1CRBNCFTRGOPC | |
| SCHEMBL72984 | 0.64 | SIRT1 (0.48) | CTRCKMT2ACFTRGOPCTSHR | |
| Charcoal, Activated SCHEMBL2025121 | 0.63 | SIRT1 (0.47) | CTRCKMT2ACFTRGOPCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |