Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842565 | 0.84 | KEAP1 (0.41) | ESR2APPCA12CA2CA4 | |
| SCHEMBL714236 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A | |
| SCHEMBL29443997 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A | |
| SCHEMBL18189724 | 0.79 | ALDH1A1 (0.79) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A | |
| SCHEMBL6925026 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A | |
| SCHEMBL5345150 | 0.79 | HPGD (0.52) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A | |
| SCHEMBL11235690 | 0.77 | CYP2A6 (0.60) | ALDH1A1HPGDHSD17B10ARBACE1 | |
| SCHEMBL6517747 | 0.77 | ESR2 (0.42) | ESR2CA12CA2CA4CA14 | |
| SCHEMBL10023983 | 0.76 | PELI1 (0.42) | ALDH1A1HPGDHSD17B10KDM1AESR2 | |
| SCHEMBL11415648 | 0.76 | BACE1 (0.56) | ALDH1A1HPGDHSD17B10BCL2L1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291692-B2 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050096452-A1 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |