Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800244 | 0.82 | CYP2A6 (0.41) | HPGDALDH1A1BCL2L1HSD17B10CA12 | |
| SCHEMBL9469214 | 0.81 | ADRA2C (0.55) | HPGDALDH1A1BCL2L1HSD17B10ESR2 | |
| SCHEMBL7570908 | 0.80 | HPGD (0.71) | HPGDALDH1A1BCL2L1HSD17B10ESR2 | |
| SCHEMBL29944266 | 0.80 | HPGD (0.71) | HPGDALDH1A1BCL2L1HSD17B10ESR2 | |
| SCHEMBL11305092 | 0.79 | CYP2A6 (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5362773 | 0.79 | ALDH1A1 (0.58) | HPGDALDH1A1BCL2L1HSD17B10ESR2 | |
| SCHEMBL11364558 | 0.78 | GABRA5 (0.44) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29429017 | 0.78 | ALDH1A1 (0.52) | HPGDALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL3841296 | 0.77 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3780798 | 0.76 | MCL1 (0.43) | HPGDALDH1A1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291692-B2 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050096452-A1 | Polyarylene oxide and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |