Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855195 | 0.85 | SIRT6 (0.64) | SIRT6ADRB1MAPTPOLBALDH1A1 | |
| SCHEMBL5386571 | 0.77 | ATM (0.45) | SIRT6MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL13934667 | 0.77 | MEN1 (0.47) | ADRB1POLBMEN1KMT2AAKR1C3 | |
| SCHEMBL16701654 | 0.77 | DDB1 (0.44) | MAPTPOLBALDH1A1CRBNMEN1 | |
| SCHEMBL6201723 | 0.76 | PTPN1 (0.43) | ADRB1MAPTPOLBALDH1A1CRBN | |
| SCHEMBL29271601 | 0.76 | SIRT6 (0.44) | SIRT6ADRB1MAPTPOLBALDH1A1 | |
| SCHEMBL5356318 | 0.75 | ALDH1A1 (0.62) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL6151230 | 0.75 | SIRT6 (0.81) | SIRT6ADRB1MAPTPOLBALDH1A1 | |
| SCHEMBL15271381 | 0.75 | SIRT6 (0.81) | SIRT6ADRB1MAPTPOLBALDH1A1 | |
| SCHEMBL29036910 | 0.74 | ADRB1 (0.49) | SIRT6ADRB1MAPTALDH1A1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160912-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR.REDDY'S LABORATORIES LTD. (IN) | 2007-01-09 | — | — | US | disclosed |
| US-7160912-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR.REDDY'S LABORATORIES LTD. (IN) | 2007-01-09 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-20060293315-A1 | Intermediates of novel heterocyclic compounds having antibacterial activity and process for their preparation | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-12-28 | — | — | US | disclosed |
| US-20040102494-A1 | Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102494-A1 | Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | CYP51A1, OXA1L, LSS | SIRT6 1528/4885ADRB1 977/4885MAPT 4571/4885 |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | OXA1L, LSS, MRPL21 | SIRT6 1445/4885ADRB1 2036/4885MAPT 4373/4885 |
| US-20060293315-A1 | Intermediates of novel heterocyclic compounds having antibacterial activity and process for their preparation | CYP51A1, OXA1L, LSS | SIRT6 1674/4885ADRB1 1946/4885MAPT 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.