Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130173 | 0.83 | TDP1 (0.33) | CA4THRBKDM4EESR1ESR2 | |
| SCHEMBL393947 | 0.83 | TDP1 (0.33) | CA4THRBKDM4EESR1ESR2 | |
| SCHEMBL28172890 | 0.81 | ESR1 (0.33) | CA4THRBKDM4EESR1ESR2 | |
| SCHEMBL106516 | 0.79 | TSHR (0.36) | CA4ESR1ESR2 | |
| SCHEMBL705119 | 0.77 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL3164541 | 0.74 | ADRA2A (0.40) | KDM4E | |
| SCHEMBL28390987 | 0.74 | TSHR (0.33) | CA4ESR1ESR2 | |
| SCHEMBL5359631 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL427067 | 0.72 | MAPT (0.35) | KDM4E | |
| SCHEMBL27707273 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7193026-B2 | Organosilicon compound-curing composition and silicone-base coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20040260048-A1 | Organosilicon compound - curing composition and silicone-base coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |