SCHEMBL393947

SCHEMBL393947

COC(C)O[Si](OC(C)OC)(OC(C)OC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
CA4 P22748 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130173 1.00 TDP1 (0.33) TDP1CA4THRBALDH1A1KDM4E
SCHEMBL5363344 0.83 CA4 (0.32) CA4THRBKDM4EESR1ESR2
SCHEMBL28172890 0.81 ESR1 (0.33) CA4THRBALDH1A1KDM4EESR1
SCHEMBL106923 0.79 TDP1 (0.37) TDP1CA4THRBALDH1A1ESR1
SCHEMBL7242289 0.74 POLB (0.33) CA4ALDH1A1KDM4EESR1ESR2
SCHEMBL7190607 0.74 POLB (0.33) CA4ALDH1A1KDM4EESR1ESR2
SCHEMBL11526330 0.74 ADRA2A (0.40) TDP1ALDH1A1KDM4E
SCHEMBL7786206 0.74 MAPT (0.36) TDP1ALDH1A1KDM4E
SCHEMBL645558 0.72 ALDH1A1 (0.35) TDP1THRBALDH1A1KDM4E
SCHEMBL5546414 0.72 KMT2A (0.36) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12104113-B2 Thermally conductive silicone composition, production method thereof, and semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-10-01 US disclosed
US-20220275265-A1 THERMALLY CONDUCTIVE SILICONE COMPOSITION, PRODUCTION METHOD THEREOF, AND SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-09-01 US disclosed
EP-4036964-A1 THERMALLY CONDUCTIVE SILICONE COMPOSITION, PRODUCTION METHOD THEREOF, AND SEMICONDUCTOR DEVICE Shin-Etsu Chemical Co., Ltd. (JP) 2022-08-03 EP disclosed
EP-2794984-B1 HEAT-TRANSFER TEXTILE INK DOW CORNING (US) 2017-09-27 EP disclosed
US-9315682-B2 Heat-transfer textile ink DOW CORNING CORPORATION (US) 2016-04-19 US disclosed
US-20150004336-A1 Heat-Transfer Textile Ink DOW CORNING CORPORATION (US) 2015-01-01 US disclosed
US-20140356590-A1 Direct Printing Composition DOW CORNING CORPORATION 2014-12-04 US disclosed
EP-2794984-A2 HEAT-TRANSFER TEXTILE INK Dow Corning Corporation (US) 2014-10-29 EP disclosed
EP-2794783-A2 DERECT PRINTING COMPOSITION Dow Corning Corporation (US) 2014-10-29 EP disclosed
EP-1957597-B1 CONTINUOUS PROCESS FOR PRODUCTION OF SILICONE PRESSURE SENSITIVE ADHESIVES DOW CORNING (US) 2014-04-30 EP disclosed
EP-0239049-B1 IMPROVED BAKEWARE RELEASE COATING DOW CORNING CORPORATION (US) 1993-04-07 EP disclosed
US-5196477-A Protective coating for metal contactor in electronic circuits SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US disclosed
US-5180771-A ROOM TEMPERATURE CURABLE ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-19 US disclosed
US-4965333-A BONDING ADHESIVE; IMPROVED SHELF LIFE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-23 US disclosed
EP-0392877-A2 Room temperature curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-17 EP disclosed
US-4721766-A Room temperature-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-01-26 US disclosed
EP-0239049-A2 Improved bakeware release coating DOW CORNING CORPORATION (US) 1987-09-30 EP disclosed
US-4677147-A Bakeware release coating DOW CORNING CORPORATION (US) 1987-06-30 US disclosed
US-4064096-A Curable, storage-stable liquid organopolysiloxane compositions RHONE-POULENC INDUSTRIES (FR) 1977-12-20 US disclosed
US-3965280-A Use of organopolysiloxane compositions which cure at ambient temperature in coating electrical and electronic devices RHONE-POULENC S.A. (FR) 1976-06-22 US disclosed