Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333351 | 0.80 | CYP17A1 (0.37) | GRM5SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL5338160 | 0.79 | CYP2C19 (0.32) | GRM5SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL5330573 | 0.73 | MAPT (0.46) | SMN1; SMN2NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL5363955 | 0.71 | KDM4E (0.43) | SMN1; SMN2NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL18633527 | 0.68 | KDM4E (0.46) | GRM5SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL26346705 | 0.66 | GRM5 (0.45) | GRM5SLC11A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15989883 | 0.64 | KDM4E (0.44) | GRM5SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL19665165 | 0.64 | NPC1 (0.38) | SMN1; SMN2NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL19289607 | 0.64 | KDM4E (0.44) | GRM5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20132487 | 0.64 | CCR1 (0.47) | SMN1; SMN2NPC1ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |