SCHEMBL20132487

SCHEMBL20132487

Cc1ccc(-c2ccc(-c3ccccc3)cc2C)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.47
CCR5 P51681 1/20 0.47
CCR8 P51685 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CYP3A4 P08684 2/20 0.46
CYP2A6 P11509 1/20 0.46
LDHA P00338 1/20 0.43
PTGS2 P35354 2/20 0.42
FLT3 P36888 2/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
PSMB5 P28074 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX5AP P20292 2/20 0.39
FEN1 P39748 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20049051 0.87 CCR1 (0.47) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL24088236 0.87 CYP3A4 (0.50) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL15506532 0.87 PSMB5 (0.46) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL21266019 0.83 CCR1 (0.50) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL16948797 0.83 LDHA (0.49) LDHAFLT3MEN1KMT2APSMB5
SCHEMBL23879663 0.82 LDHA (0.47) LDHAFLT3MEN1KMT2APSMB5
SCHEMBL24395066 0.82 CCR1 (0.48) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL23956294 0.81 LDHA (0.40) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL20477182 0.81 PTGS2 (0.49) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL12359222 0.81 CYP3A4 (0.61) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 US disclosed
US-11142538-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-12 US disclosed
US-20200361975-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-19 US disclosed
US-10680187-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-10672998-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-02 US disclosed
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-02-13 US disclosed
US-20180130962-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 CCR1 1241/4885CCR5 456/4885CCR8 2150/4885
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, MLX CCR1 802/4885CCR5 1443/4885CCR8 1729/4885
US-20200361975-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, L1CAM, LEF1 CCR1 1383/4885CCR5 2168/4885CCR8 1196/4885
US-20180130962-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, ORC3, LEF1 CCR1 2902/4885CCR5 3010/4885CCR8 4028/4885
US-11142538-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 CCR1 1241/4885CCR5 456/4885CCR8 2150/4885
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC CCR1 4668/4885CCR5 4175/4885CCR8 4221/4885
US-10672998-B2 Organic electroluminescent materials and devices LBR, HDAC3, SIRT3 CCR1 518/4885CCR5 648/4885CCR8 1137/4885
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 CCR1 1908/4885CCR5 1670/4885CCR8 2654/4885
US-10680187-B2 Organic electroluminescent materials and devices TYR, ORC3, LEF1 CCR1 2902/4885CCR5 3010/4885CCR8 4028/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 CCR1 571/4885CCR5 1054/4885CCR8 1378/4885
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM CCR1 744/4885CCR5 1474/4885CCR8 1782/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 CCR1 1383/4885CCR5 2168/4885CCR8 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.