Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | STAT1 | P42224 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363950 | 0.79 | GRM5 (0.40) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5333351 | 0.78 | CYP17A1 (0.37) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL5330573 | 0.74 | MAPT (0.46) | CYP2C19KDM4EKMT2AMEN1ESRRA | |
| SCHEMBL5338164 | 0.72 | NPC1 (0.53) | CYP2C19KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL5313526 | 0.64 | NOTUM (0.34) | KDM4EKMT2AMEN1ESRRAALDH1A1 | |
| SCHEMBL5334228 | 0.64 | LMNA (0.44) | CYP2C19KDM4EESRRAALDH1A1MAPT | |
| SCHEMBL14263740 | 0.62 | PHGDH (0.46) | CYP2C19KDM4EKMT2AMEN1ESRRA | |
| SCHEMBL20424422 | 0.61 | CYP2C19 (0.38) | CYP2C19KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL19618901 | 0.60 | ESR2 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL22111431 | 0.60 | ESR2 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |