Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363950 | 0.80 | GRM5 (0.40) | NPC1RAB9AMAPTSMN1; SMN2BTK | |
| SCHEMBL5338160 | 0.78 | CYP2C19 (0.32) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL5330573 | 0.72 | MAPT (0.46) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL5333352 | 0.72 | ALDH1A1 (0.48) | MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL10562053 | 0.67 | CFTR (0.46) | CYP17A1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10557401 | 0.65 | GAA (0.45) | CYP17A1NPC1RAB9ATP53MAPT | |
| SCHEMBL18228013 | 0.65 | CFTR (0.43) | SMN1; SMN2KCNA5GAACFTRSLC6A2 | |
| SCHEMBL24534337 | 0.63 | SLC2A1 (0.68) | CYP17A1SLC2A1NPC1RAB9AMKNK1 | |
| SCHEMBL18228420 | 0.63 | CFTR (0.44) | SMN1; SMN2CYP2A6KCNA5GAACFTR | |
| Chloromethane SCHEMBL10559562 | 0.62 | GAA (0.43) | NPC1RAB9ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |