Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755409 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL27708697 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL18024028 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL13301165 | 0.70 | ALDH1A1 (0.42) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL5760589 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL2185175 | 0.68 | CA1 (0.42) | ALDH1A1CA1CA2POLBKMT2A | |
| SCHEMBL30173328 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL19402821 | 0.67 | ALDH1A1 (0.40) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL16508745 | 0.67 | CA1 (0.46) | ALDH1A1CA1CA2POLBFKBP1A | |
| SCHEMBL21361488 | 0.67 | ALDH1A1 (0.49) | ALDH1A1CA1CA2POLBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244744-B2 | Piperidines | ICAGEN, INC. (US) | 2007-07-17 | — | — | US | disclosed |