Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093845 | 1.00 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL2297383 | 1.00 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL1204753 | 1.00 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL30803745 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL3725398 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL28418766 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL28675045 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL1903588 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL7895556 | 0.95 | LMNA (0.42) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL27811476 | 0.90 | LMNA (0.33) | LMNADNM1TSHRTHRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235510-B2 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2007-06-26 | — | — | US | disclosed |
| US-20050164296-A1 | reaction product of a meso-porous organofunctional silica and a ligand; organofunctional silica is prepared from an alkyl silicate and at least one organofunctional silane which contains a group reactive with ligand functional group | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2005-07-28 | — | — | US | disclosed |
| EP-1360004-B1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2005-05-25 | — | — | EP | disclosed |
| EP-1360004-A1 | CATALYSTS | Johnson Matthey PLC (GB) | 2003-11-12 | — | — | EP | disclosed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |
| WO-2002066159-A1 | CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2002-08-29 | — | — | WO | disclosed |