Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121414 | 0.78 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL48955 | 0.76 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL13835936 | 0.75 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL18125 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL13621387 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL13621398 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL211428 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL11488036 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL2248044 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3CA4 | |
| SCHEMBL2349819 | 0.73 | ESR1 (0.35) | ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-3060236-B1 | POLYNUCLEOTIDE, POLYPEPTIDE WITH IMMUNOSUPPRESIVE ACTIVITY, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING A POLYPETIDE WITH IMMUNOSUPPRESIVE ACTIVITY AND FOR PREVENTING OR TREATING CONDITIONS THAT REQUIRE IMMUNOSUPPRESION | FUND BUTANTAN (BR) | 2020-12-02 | — | — | EP | disclosed |
| US-10081660-B2 | Polynucleotide, polypeptide with immunosuppressive activity, expression cassette, expression vector, host cell, pharmaceutical composition, methods for producing a polypeptide with immunosuppressive activity and for preventing or treating conditions that require immunosuppression, and use of a polypeptide | FUNDAÇÃO BUTANTAN (BR) | 2018-09-25 | — | — | US | disclosed |
| US-20160311869-A1 | Polynucleotide, Polypeptide with Immunosuppressive Activity, Expression Cassette, Expression Vector, Host Cell, Pharmaceutical Composition, Methods for Producing a Polypeptide with Immunosuppressive Activity and for Preventing or Treating Conditions That Require Immunosuppression, and Use of a Polypeptide | FUNDAÇÃO BUTANTAN (BR) | 2016-10-27 | — | — | US | disclosed |
| EP-3060236-A1 | POLYNUCLEOTIDE, POLYPEPTIDE WITH IMMUNOSUPPRESIVE ACTIVITY, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCING A POLYPETIDE WITH IMMUNOSUPPRESIVE ACTIVITY AND FOR PREVENTING OR TREATING CONDITIONS THAT REQUIRE IMMUNOSUPPRESION AND USE OF A POLYPEPTIDE | Fundação Butantan (BR) | 2016-08-31 | — | — | EP | disclosed |
| US-9099744-B2 | Particulate porous carbon material and use thereof in lithium cells | BASF SE (DE) | 2015-08-04 | — | — | US | disclosed |
| WO-2015058275-A1 | POLYNUCLEOTIDE, POLYPEPTIDE WITH IMMUNOSUPPRESIVE ACTIVITY, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCING A POLYPETIDE WITH IMMUNOSUPPRESIVE ACTIVITY AND FOR PREVENTING OR TREATING CONDITIONS THAT REQUIRE IMMUNOSUPPRESION AND USE OF A POLYPEPTIDE | CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) | 2015-04-30 | — | — | WO | disclosed |
| US-8992801-B2 | Electroactive material, and use thereof in anodes for lithium-ion cells | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| EP-2415106-B1 | ELECTROACTIVE MATERIAL AND ITS USE IN ANODES FOR LITHIUM-ION CELLS | BASF SE (DE) | 2014-08-20 | — | — | EP | disclosed |
| US-8680203-B2 | Process for producing a particulate nanocomposite material | BASF SE (DE) | 2014-03-25 | — | — | US | disclosed |
| US-5700938-A | Intermediates for imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0627433-A1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | Eisai Co., Ltd. (JP) | 1994-12-07 | — | — | EP | disclosed |