Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026664 | 0.81 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL2233576 | 0.79 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL121414 | 0.78 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL7565872 | 0.77 | ESR1 (0.38) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL48955 | 0.76 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL11034567 | 0.75 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL332855 | 0.75 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL4445118 | 0.75 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL2796775 | 0.75 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL536490 | 0.74 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1066 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12614943-B2 | Electrical operating means having an insulation system, and method for producing the insulation system | SIEMENS AKTIENGESELLSCHAFT (DE) | 2026-04-28 | — | — | US | claimed |
| US-20240400858-A1 | HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS | SOLSTICE ADVANCED MATERIALS US, INC. | 2024-12-05 | — | — | US | claimed |
| WO-2024243005-A1 | HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS | HONEYWELL INTERNATIONAL INC. (US) | 2024-11-28 | — | — | WO | claimed |
| CN-117624698-A | Preparation method and application of polydiphenyl siloxane friction layer for friction nano generator | 中国林业科学研究院林产化学工业研究所 | 2024-03-01 | — | — | CN | claimed |
| CN-117126539-A | Low-permeability double-group organic silica gel composition | 浙江励德有机硅材料有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-116751509-A | Ultraviolet light cured heat-resistant yellowing-resistant coating and preparation method thereof | 东周化学工业(昆山)有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-116047807-A | Mini-LED direct type backlight module with staggered non-uniform arrangement | 福州大学 | 2023-05-02 | — | — | CN | claimed |
| CN-114958369-B | Organic silicon coated quantum dot material and preparation method and application thereof | 广东欧迪明光电科技股份有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-113730297-B | Pearlescent no-wash hair care essence | 广州市衡拓贸易有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115778855-A | Lipstick and its preparation method | 上海臻臣化妆品有限公司 | 2023-03-14 | — | — | CN | claimed |
| WO-1994021224-A1 | COSMETIC OR TOPICAL USE OF AN AQUEOUS DISPERSION BASED ON NON-VOLATILE ORGANOPOLYSILOXANES AND AN ACRYLAMIDE OR HOMOPOLYMERIC COPOLYMER TYPE CROSS-LINKED METHACRYLOYLOXYETHYL TRIMETHYLAMMONIUM CHLORIDE POLYMER | L'OREAL (FR) | 1994-09-29 | — | — | WO | claimed |
| EP-0522776-B1 | Polymerisation reactor and polymerisation process | DOW CORNING SA (BE) | 1994-08-03 | — | — | EP | claimed |
| US-5319120-A | Mixing with pressurized gas to produce foaming prior to polymerization | DOW CORNING S.A. (BE) | 1994-06-07 | — | — | US | claimed |
| EP-0424260-B1 | Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer | OREAL (FR) | 1993-12-15 | — | — | EP | claimed |
| EP-0557512-A1 | UTILIZATION IN COSMETIC OR TOPICAL APPLICATIONS OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND A CROSSLINKED COPOLYMER OF ACRYLAMIDE/NEUTRALIZED 2-ACRYLAMIDO 2-METHYLPROPANE SULFONIC ACID. | OREAL (FR) | 1993-09-01 | — | — | EP | claimed |
| WO-1993005762-A1 | UTILIZATION IN COSMETIC OR TOPICAL APPLICATIONS OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND A CROSSLINKED COPOLYMER OF ACRYLAMIDE/NEUTRALIZED 2-ACRYLAMIDO 2-METHYLPROPANE SULFONIC ACID | L'OREAL (FR) | 1993-04-01 | — | — | WO | claimed |
| EP-0522776-A1 | Polymerisation reactor and polymerisation process | DOW CORNING S.A. (BE) | 1993-01-13 | — | — | EP | claimed |
| US-5160730-A | USE OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND ON A CROSSLINKED AMMONIUM ACRYLATE/ACRYLAMIDE COMPOLYMER IN COSMETICS, FOR THE TREATMENT OF HAIR OR THE SKIN AND/OR IN DERMATOLOGY | L'OREAL (FR) | 1992-11-03 | — | — | US | claimed |
| EP-0424260-A1 | Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer | L'OREAL (FR) | 1991-04-24 | — | — | EP | claimed |
| US-4177182-A | MINIMIZATION OF LEACHING OF PLASTICIZER IN MEDICAL EQUIPMENT | TERUMO CORP. (JP) | 1979-12-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12614943-B2 | Electrical operating means having an insulation system, and method for producing the insulation system | SCO2, RAE1, FTO | ESR1 22/4885ESR2 40/4885NR1H2 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.