SCHEMBL211428

SCHEMBL211428

C[Si](C)(O[SiH3])c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TSHR P16473 2/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026664 0.81 ESR1 (0.34) ESR1ESR2
SCHEMBL2233576 0.79 ESR1 (0.39) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL121414 0.78 ESR1 (0.42) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL7565872 0.77 ESR1 (0.38) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL48955 0.76 ESR1 (0.41) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL11034567 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL332855 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL4445118 0.75 ESR1 (0.33) ESR1ESR2
SCHEMBL2796775 0.75 ESR1 (0.44) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL536490 0.74 ESR1 (0.39) ESR1ESR2NR1H2NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1066 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12614943-B2 Electrical operating means having an insulation system, and method for producing the insulation system SIEMENS AKTIENGESELLSCHAFT (DE) 2026-04-28 US claimed
US-20240400858-A1 HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS SOLSTICE ADVANCED MATERIALS US, INC. 2024-12-05 US claimed
WO-2024243005-A1 HIGH CRACK THRESHOLD PLANARIZING COATINGS AND PROCESSES TO FILL WIDE AND DEEP TRENCHES FOR SILICONE WAFERS HONEYWELL INTERNATIONAL INC. (US) 2024-11-28 WO claimed
CN-117624698-A Preparation method and application of polydiphenyl siloxane friction layer for friction nano generator 中国林业科学研究院林产化学工业研究所 2024-03-01 CN claimed
CN-117126539-A Low-permeability double-group organic silica gel composition 浙江励德有机硅材料有限公司 2023-11-28 CN claimed
CN-116751509-A Ultraviolet light cured heat-resistant yellowing-resistant coating and preparation method thereof 东周化学工业(昆山)有限公司 2023-09-15 CN claimed
CN-116047807-A Mini-LED direct type backlight module with staggered non-uniform arrangement 福州大学 2023-05-02 CN claimed
CN-114958369-B Organic silicon coated quantum dot material and preparation method and application thereof 广东欧迪明光电科技股份有限公司 2023-04-14 CN claimed
CN-113730297-B Pearlescent no-wash hair care essence 广州市衡拓贸易有限公司 2023-03-31 CN claimed
CN-115778855-A Lipstick and its preparation method 上海臻臣化妆品有限公司 2023-03-14 CN claimed
WO-1994021224-A1 COSMETIC OR TOPICAL USE OF AN AQUEOUS DISPERSION BASED ON NON-VOLATILE ORGANOPOLYSILOXANES AND AN ACRYLAMIDE OR HOMOPOLYMERIC COPOLYMER TYPE CROSS-LINKED METHACRYLOYLOXYETHYL TRIMETHYLAMMONIUM CHLORIDE POLYMER L'OREAL (FR) 1994-09-29 WO claimed
EP-0522776-B1 Polymerisation reactor and polymerisation process DOW CORNING SA (BE) 1994-08-03 EP claimed
US-5319120-A Mixing with pressurized gas to produce foaming prior to polymerization DOW CORNING S.A. (BE) 1994-06-07 US claimed
EP-0424260-B1 Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer OREAL (FR) 1993-12-15 EP claimed
EP-0557512-A1 UTILIZATION IN COSMETIC OR TOPICAL APPLICATIONS OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND A CROSSLINKED COPOLYMER OF ACRYLAMIDE/NEUTRALIZED 2-ACRYLAMIDO 2-METHYLPROPANE SULFONIC ACID. OREAL (FR) 1993-09-01 EP claimed
WO-1993005762-A1 UTILIZATION IN COSMETIC OR TOPICAL APPLICATIONS OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND A CROSSLINKED COPOLYMER OF ACRYLAMIDE/NEUTRALIZED 2-ACRYLAMIDO 2-METHYLPROPANE SULFONIC ACID L'OREAL (FR) 1993-04-01 WO claimed
EP-0522776-A1 Polymerisation reactor and polymerisation process DOW CORNING S.A. (BE) 1993-01-13 EP claimed
US-5160730-A USE OF AN AQUEOUS DISPERSION BASED ON ORGANOPOLYSILOXANES AND ON A CROSSLINKED AMMONIUM ACRYLATE/ACRYLAMIDE COMPOLYMER IN COSMETICS, FOR THE TREATMENT OF HAIR OR THE SKIN AND/OR IN DERMATOLOGY L'OREAL (FR) 1992-11-03 US claimed
EP-0424260-A1 Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer L'OREAL (FR) 1991-04-24 EP claimed
US-4177182-A MINIMIZATION OF LEACHING OF PLASTICIZER IN MEDICAL EQUIPMENT TERUMO CORP. (JP) 1979-12-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12614943-B2 Electrical operating means having an insulation system, and method for producing the insulation system SCO2, RAE1, FTO ESR1 22/4885ESR2 40/4885NR1H2 2821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.