Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365964 | 0.78 | CYP11B2 (0.47) | AR | |
| SCHEMBL4920032 | 0.76 | AR (0.58) | ARPGRRXRARXRBRXRG | |
| SCHEMBL21416825 | 0.74 | AR (0.73) | ARPGRRXRARXRBRXRG | |
| SCHEMBL3075671 | 0.72 | AR (0.57) | ARPGRRXRARXRBRXRG | |
| SCHEMBL4921058 | 0.72 | ALDH1A1 (0.45) | — | |
| SCHEMBL6466194 | 0.71 | AR (0.59) | ARPGRRXRARXRBRXRG | |
| SCHEMBL409108 | 0.71 | AR (0.74) | ARPGR | |
| SCHEMBL12804480 | 0.71 | AR (1.00) | ARPGR | |
| SCHEMBL5711220 | 0.70 | AR (0.72) | ARPGRRXRARXRBRXRG | |
| SCHEMBL6397627 | 0.69 | AR (0.76) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |