Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 8/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330691 | 0.91 | HTR6 (0.46) | MAPTHTR6LMNAMAPK1HTT | |
| SCHEMBL5327797 | 0.89 | HTR6 (0.49) | HTR6PTGDR2CYP3A4CYP2D6HTR2A | |
| SCHEMBL5364941 | 0.85 | HTR6 (0.44) | MAPTHTR6CASRLMNAMAPK1 | |
| SCHEMBL5332078 | 0.84 | HTR6 (0.53) | HTR6LMNA | |
| SCHEMBL5331491 | 0.83 | HTR6 (0.52) | HTR6LMNAPTGDR2CYP3A4CYP2D6 | |
| SCHEMBL5332897 | 0.83 | HTR6 (0.51) | HTR6LMNAHTTPTGDR2PTGDR | |
| SCHEMBL5331426 | 0.82 | HTR6 (0.43) | MAPTHTR6PTGDR2PTGDR | |
| SCHEMBL5331999 | 0.81 | HTR6 (0.51) | MAPTHTR6PTGDR2PTGDR | |
| SCHEMBL5326882 | 0.81 | HTR6 (0.42) | MAPTHTR6LMNAHTTSMN1; SMN2 | |
| SCHEMBL5326308 | 0.81 | NOD1 (0.45) | HTR6LMNAHTTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |