Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327800 | 0.91 | HTR6 (0.55) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL5330693 | 0.90 | HTR6 (0.53) | HTR6MAPT | |
| SCHEMBL5364940 | 0.85 | MAPT (0.42) | HTR6MAPTCASRLMNAMAPK1 | |
| SCHEMBL5332081 | 0.85 | HTR6 (0.50) | HTR6 | |
| SCHEMBL5331494 | 0.85 | HTR6 (0.50) | HTR6LMNACYP3A4CYP2D6 | |
| SCHEMBL5331429 | 0.84 | HTR6 (0.42) | HTR6 | |
| SCHEMBL5326312 | 0.83 | NOD1 (0.42) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5332899 | 0.83 | HTR6 (0.60) | HTR6 | |
| SCHEMBL5326887 | 0.83 | HTR6 (0.40) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5332004 | 0.81 | HTR6 (0.58) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |