SCHEMBL5365534

SCHEMBL5365534

Cc1cc(O)n(-c2ccc(S(=O)(=O)CCOS(=O)(=O)OCCS(=O)(=O)c3ccc(-n4nc(C)cc4O)cc3)cc2)n1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PTGS2 P35354 3/20 0.41
POLB P06746 4/20 0.40
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
LMNA P02545 3/20 0.38
PKM P14618 1/20 0.38
TERT O14746 1/20 0.37
RXFP1 Q9HBX9 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.35
APEX1 P27695 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
STAT1 P42224 1/20 0.34
PTGS1 P23219 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5103396 0.93 ALOX5 (0.41) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL15346504 0.84 ALDH1A1 (0.43) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL2911214 0.80 ALOX5 (0.50) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL15346505 0.79 ALDH1A1 (0.42) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL27783698 0.76 ALOX5 (0.42) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL23403562 0.76 PTGS2 (0.66) ALOX5PTGS2PTGS1
SCHEMBL23400020 0.73 SMN1; SMN2 (0.58) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL1415165 0.71 SMN1; SMN2 (0.47) ALOX5PTGS2POLBALDH1A1SMN1; SMN2
SCHEMBL28620570 0.70 MAPK1 (0.47) POLBALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL11441588 0.70 CYP1A2 (0.47) POLBALDH1A1SMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-7135266-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2006-11-14 US disclosed
US-20060228640-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED 2006-10-12 US disclosed
US-20060042117-A1 Method and device for carrying out chemical and physical methods CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-03-02 US disclosed
US-20030083410-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE ( BVI) LIMITED 2003-05-01 US disclosed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US disclosed
US-6469147-B2 DIAZOTIZATION CLARIANT FINANCE (BVI) LIMITED (VG) 2002-10-22 US disclosed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US disclosed
US-20010029294-A1 Preparation of azo colorants in microreactors CLARIANT INTERNATIONAL LTD. 2001-10-11 US disclosed